HIV-related stigma and universal testing and treatment for HIV prevention and care: design of an implementation science evaluation nested in the HPTN 071 (PopART) cluster-randomized trial in Zambia and South Africa

Hargreaves, J; Stangl, A; Bond, V; Hoddinott, G; Krishnaratne, S; Mathema, H; Moyo, M; Viljoen, L; Brady, L; Sievwright, K; Horn, L; Sabapathy, K; Ayles, H; Beyers, N; Bock, P; Fidler, S; Griffith, S; Seeley, J; Hayes, R Health Policy and Planning, 2016; heapol.oxfordjournals.org/content/early/2016/07/02/heapol.czw071.full?key...

HIV-related stigma and discrimination can act as barriers to the implementation of successful HIV prevention programmes.

Studies measuring the impact of stigma on HIV prevention and treatment programmes are rare. This study is a mixed-method evaluation nested within HPTN 071/PopART, a three-arm trial comparing universal door-to-door delivery of HIV testing and referral to prevention and treatment services, accompanied by either an immediate offer of anti-retroviral treatment to people living with HIV (PLHIV) regardless of clinical status, or an offer of treatment in-line with national guidelines, with a standard-of-care control arm. The primary outcome of interest for the trial is HIV incidence.

This study will evaluate the extent to which HIV-related stigma affects and is affected by the implementation of a comprehensive combination HIV prevention intervention including a universal test and treatment approach.

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