The cost-effectiveness of multi-purpose HIV and pregnancy prevention technologies in South Africa

Matthew Quaife, Fern Terris-Prestholt, Robyn Eakle, Maria A. Cabrera Escobar, Maggie Kilbourne-Brook, Mercy Mvundura, Gesine Meyer-Rath, Sinead Delany-Moretlwe and Peter Vickerman Journal of the International AIDS Society, 2018; Read the full paper online

A number of antiretroviral HIV prevention products are efficacious in preventing HIV infection. However, the sexual and reproductive health needs of many women extend beyond HIV prevention, and research is ongoing to develop multi-purpose prevention technologies (MPTs) that offer dual HIV and pregnancy protection. We do not yet know if these products will be an efficient use of constrained health resources. 

This study, which may be the first of its kind, estimated the cost-effectiveness of combinations of candidate multi-purpose prevention technologies (MPTs) in South Africa among general population women and female sex workers (FSWs). The results suggest that MPTs will be cost-effective among higher incidence FSWs or young women, but not among lower incidence older women. More work is needed to make attractive MPTs available to potential users who could use them effectively.

Related resource

STRIVE Learning Lab: Sex, risk, and preferences: Using discrete choice experiments to estimate the impact and cost-effectiveness of multipurpose HIV prevention products in South Africa


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