Preferences for ARV-based HIV prevention methods among men and women, adolescent girls and female sex workers in Gauteng Province, South Africa: a protocol for a discrete choice experiment

Matthew Quaife, Robyn Eakle, Maria Cabrera, Peter Vickerman, Motlalepule Tsepe, Fiona Cianci, Sinead Delany-Moretlwe, Fern Terris-Prestholt BMJ Open, 2016; Read full paper online

For the past few decades, condoms have been the main method of HIV prevention. Recent advances in antiretroviral (ARV)-based prevention products have substantially changed the prevention landscape, yet little is known about how popular these products will be among potential users, or whether new methods might be used in conjunction with, or instead of, condoms.

This study uses a discrete choice experiment (DCE) to:

  1. explore potential users' preferences regarding HIV prevention products
  2. quantify the importance of product attributes
  3. predict the uptake of products to inform estimates of their potential imapact on the HIV epidemic in South Africa

The study gathers data from four populations: 200 women, 200 men, 200 adolescent girls (aged 16-17 years) and 200 female sex workers. The DCE attributes and design will be developed through a literature review, supplemented by a thematic analysis of qualitative focus group discussions. Extensive piloting will be carried out through semistructured interviews. 

Policy recommendations will be drawn from the findings, in particular to inform mathematical models to evaluate the impact and cost-effectiveness of a range of new prevention products.


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